PLOS Biology, 13 6 , e Jilka, R. Journal of Bone and Mineral Research, 31 7 , — Landis, S. A call for transparent reporting to optimize the predictive value of preclinical research. Nature, , — Leung, V. Macleod, M. Biomedical research: Increasing value, reducing waste. The Lancet, , — Simmons, J. Psychological Science, 22 11 , — Your email address will not be published.
First we need to confirm, that you're human. Evgeny Bobrov supports biomedical researchers with managing and sharing their data.
He offers consulting and training, and develops strategies for the provision of research data management RDM services. One of his core interests is the diversification of RDM services, to cater for the needs of both basic and clinical researchers within the same institution. Bold ideas and critical thoughts on science. Evgeny Bobrov Increasing value in biomedical research 6 August doi References Avey, M. Submit a Comment Cancel reply Your email address will not be published. Author info Evgeny Bobrov supports biomedical researchers with managing and sharing their data.
Cite as Bobrov, E. Elephant in the Lab. Wolters Kluwer Medknow has a policy that changes will not be made after publication of an article without following accepted procedures for making corrections to the scientific record. While advertisements are crucial to this journal to be able to keep all content free for everyone, ethical considerations are in place to ensure the integrity of the journal and its content: "Pop-up" and "banner" ads appear on a random, rotating basis.
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Methods: One hundred and eighty-one K. Results: Phenotypic testing also showed a high level of antibiotic resistance, while the genotypic methods indicated the presence and expression of carbapenemase genes. Conclusions: The findings suggest revisions in the current antibiotic therapy protocols, considering the high expression level of resistant carbapenemases to K. Evaluation of two types of vitamin D receptor gene morphism in patients with type 2 diabetes and obesity Sahar Azizi; Rodabe Behzadi Andohjerdi; Hamidreza Mohajerani Volume 8, Issue 1, pp.
Many people suffer from diabetes and obesity. The effects of renoprotective vitamin Read More Introduction: Diabetes is the most common endocrine disorder that affects many people each year.
The effects of renoprotective vitamin D and its analogues in chronic kidney diseases, including diabetic nephropathy, have been reported. The aim of this study was to investigate the rs and rs polymorphisms of vitamin D receptor gene GDR in patients with type 2 diabetes and obesity. After collecting clinical data and performing Laboratory tests, DNA samples were extracted from blood samples by phenol chloroform method, and polymorphisms in specimens were examined by specific genotypes. Data were analyzed by SPSS22 software. Results: There was no correlation between Taq1 and Fok1 polymorphisms with both healthy and healthy patients.
Conclusion: No evidence was found that VDR gene polymorphisms play a role in the risk of type 2 diabetes and obesity in Iranian subjects. Further studies in prospective cohort studies should be performed to determine the genome-wide association to evaluate the direct effect of these polymorphisms on type 2 diabetes.
Evaluation of different herbicides on weed control, yield and yield components of soybean Glycine max L. Read More In order to investigate the effect of weed control with common herbicides on yield and components of soybean yield Glycin max L. The treatments consisted of Ethalfluralin, Imazethapyr, Trifluralin, Metribuzin, Bentazone and Alacolor herbicides with and without weed control. The results showed that the number of pods per plant, biological yield, grain yield and soybean protein percentage were statistically significant, but for chlorophyll index, seed weight and oil percent grain, the difference was not statistically significant.
The highest number of pods per plant The results of the analysis of variance showed that the treatments had a significant difference in terms of the percentage of the effect of herbicide, density and total weed dry weight. The results showed that one month after spraying, the Trifluralin and Ethalfluralin herbicides had the highest effect on the weed control and two months after spraying, the rest of the treatments also showed their effect and all herbicide treatments were in one group.
In this study, all weed control treatments significantly reduced the density and dry weight of weeds than without control, but their effect was less than hand weeding. The highest grain yield kg. Poinsettia's brilliant red floral display held against rich green foliage has made this unlikely species Read More The poinsettia's species name pulcherrima means "most beautiful" and that it is! Poinsettia's brilliant red floral display held against rich green foliage has made this unlikely species a holiday favorite. Its appealing presentation of the traditional Christmas colors has so endeared poinsettia that it is now second only to the Christmas tree as the most popular holiday plant.
Studies have shown that rooting substrate is one of the effective factors at rooting of hard rhizogenetic plant such as poinsettia. The purpose ofthis studyis todetermine an appropriate concentration of salicylic acid SA on rooting of poinsettia. The obtained results show that salicylic acid treatments have caused the increase of percent of rooting. The use of Salicylic acid caused a positive effect on rooting.
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The callus percentage was obtained in control and treatments. This study shows that plant growth regulators salicylic acid have a profound influence on rooting of poinsettia. Read More Objective: The inoculation of substrates with arbuscular mycorrhizal fungi AMF is one of the most important effective strategies applied and one of the aims of sustainable agriculture. Methods: This experiment was conducted to evaluate the effects of AMF inoculation 0, 2. Results: The results showed that AMF has a significant and positive effect on the studied traits compared to the control.
Water use efficiency, antioxidant capacity and total phenol content were 1. The results showed the significant and positive symbiosis between Glomus mosseae and zinnia bedding plants, which led to improvement of flowers quality. Desertification is more related to social and anthropogenic issues than natural causes Read More Today one of the ecological crisis is the phenomenon of desertification that affecting the world.
Desertification is more related to social and anthropogenic issues than natural causes and it becomes more important over the time.
Monitoringis the systematic collection and analysis of information as a project progresses. The results of the analysis showed that desertification benchmarks and indicators in the three periods had a nonlinear trend of desertification process in the region so that the numerical value is equal to 2. Among the indicators studied, aridity and annual precipitation indicators were maximum effect with values 3.
After analysis of data we understanding that in the many years we had in warning about indicators but we located in not warning years in and with climate benchmark. We find that region is not in warning about SAR indicator in all years of study and we are in warning about precipitation indicator in all years except in region. Read More A purpose of Zagros forests preservation plan is to reduce degradation factors through empowering woodman beneficiaries and underdevelopment of rural forested areas which appear as scattered agronomies inside and in forest margins, trees cutting for power supply, trees cutting for hay supply or making coal in forested regions.
Therefore, natural resources experts believe that, by creation or improvement of sustainable occupation and increasing economic power of woodman families, current trend of degradation would be controlled and degradation factors would decrease by conducting rural youth population toward the jobs with lower dependence to forest. So, this plan with purpose of preservation, restoration and principled operation of natural resources and in order to study as participatory evaluation was carried out that, the results of this plan were suggested as a number of multi-stage solutions for implementation.
Pregnancy toxemia is a metabolic disorder characterized Read More Thin ewes or very over-conditioned ewes and ewes carrying multiple pregnanciesare more likely to develop pregnancy toxemia ketosis. Pregnancy toxemia is a metabolic disorder characterized by hypoglycemia and hyperketonemia resulting from incapacity of the ewes to maintain adequate energy balance usually in the last weeks. Available information about pregnancy toxemia focuses mainly on pathogenic mechanisms and clinical features, early diagnosis, and therapeutic options.
However, the pathophysiology and metabolic changes of this disorder remain poorly understood. An immediate and accurate diagnosis usually increases the possibility for their successive treatment and prevention. The objective of this review was to increase awareness of the disease, its likely cause, and practical treatment and prevention measures.
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Histamine is a mediator released Read More Histamine is synthesized via histidine decarboxylase HDC in wide types of immune cells and is involved in abundant physiologic and pathologic processes. Histamine is a mediator released during inflammatory reactions, such as food allergy. Food allergy is immunological reactions to 'fight off' specific allergens within food in susceptible individuals. The aim of this study is investigation of the histamine hemostasis and food allergy to discover the relationship between them.